Real Madrid youngster Borja Mayoral will be given his chance in attack against Real Sociedad with Cristiano Ronaldo and Karim Benzema both out.
Zinedine Zidane has been forced to use the full depth of his squad for the game in Anoeta due to a number of absences that also includes Toni Kroos in midfield and Marcelo, which sees Theo Hernandez start at left back.
Real are aiming to equal the record of 73 consecutive games scoring, set by Santos, and also get back on track after drawing their last two LaLiga matches.
Sociedad meanwhile are in strong form having won their opening three LaLiga matches.
Real Madrid lineup: Keylor; Carvajal, Varane, Ramos, Theo; Modric, Casemiro, Isco; Bale, Mayoral and Asensio.
Real Sociedad lineup: Rulli; Odriozola, Aritz Elustondo, Llorente, Kevin; Xabi Prieto, Illarramendi, Zurutuza; Januzaj, Willian Jose and Canales