Arsenal have the toughest draw on paper, having drawn Italian powerhouse Napoli.
Their city neighbours Chelsea, face Czech club Slavia Prague. There is also an all Spanish affair with Villareal playing Valencia.
Arsenal – Napoli – Q1
Villareal – Valencia – Q2
Benfica – Eintracht Frankfurt – Q3
Slavia Prague – Chelsea – Q4
Q3 – Q4
The first leg matches will be played on April 11, with the return games taking place on April 18.